Tenant notification fact sheet for carbon tetrachloride. Small fires close to stored silicon tetrachloride may be extinguished using carbon dioxide, dry chemical extinguishers, or. The most recent work in this field has inaugurated a third revolution in the study of carbon tetrachloride hepatotoxicity. Releases of carbon tetrachloride in quantities equal to or greater than the reportable quantity rq of 10 pounds are subject to reporting to the national response center under cercla, section 304 sara title. Carbon tetrachloride wisconsin department of health services. Substance name carbon tetrachloride casrn 56235 last revised 03312010 the rfd is an estimate with uncertainty spanning perhaps an order of magnitude of a daily oral exposure to the human population including sensitive subgroups that is likely to be without an appreciable risk of deleterious effects during a lifetime. Carbon tetrachloride problem formulation assessing and. In case of skin contact wash off with soap and plenty of water. Before 1970, carbon tet was widely used as a cleaning fluid in home and industry. Carbon tetrachloride is practically nonflammable at ambient temperatures. Carbon tetrachloride, also known by many other names the most notable being tetrachloromethane, also recognised by the iupac, carbon tet in the cleaning industry, halon104 in firefighting, and refrigerant10 in hvacr is an organic compound with the chemical formula ccl 4. From the departments of pharmacology, vanderbilt university school of medicine, nashville, and johns hopkins university, baltimore.
Carbon tetrachloride ccl4 was once commonly used as a cleaning agent and remains an important compound in chemical industry. Identification product name carbon tetrachloride cat no. Carbon tetrachloride is a manufactured chemical that does not occur naturally. Carbon tetrachloride has a low potential to bioconcentrate. Chemical product and company identification boc gases, division of the boc group, inc. There is sufficient evidence in experimental animals for the carcinogenicity of carbon tetrachloride.
Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Carbon tetrachloride and mixtures containing it with the exception of chemicals containing unavoidable residues of carbon tetrachloride that do not result in atmospheric concentrations of carbon tetrachloride greater than 10 ppm are banned from consumer products. Integrated risk information system iris march 2010. Uses advised against food, drug, pesticide or biocidal product use. In vitro, dna binding of carbon tetrachloride is observed in several cellular systems. Safety data sheet northwest missouri state university. Carbon tetrachloride ccl 4 activity is defined herein as the ratio in percent of the weight of ccl 4 adsorbed by an activated carbon sample to the weight of the sample, when the carbon is saturated with ccl 4 under conditions listed in this test method. Carbon tetrachloride definition and meaning collins english. Scorecards chemical profile on carbon tetrachloride. This fact sheet is provided to fulfill new york state department of health requirements for preparation of generic fact sheets under article 27 title 24, section 272405 of the environmental conservation law.
It is a colourless liquid with a sweet smell that can be detected at low levels. It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. If inhaled if breathed in, move person into fresh air. Carbon tetrachloride carbon tet is a nonflammable colorless liquid with a heavy, sweet odor. Carbon tet is still used to manufacture propellants and other industrial chemicals. Return to the risk evaluation page for carbon tetrachloride. The problem formulation document will be available for comment until august 16, 2018 in the docket epahqoppt20160733. Carbon tetrachloride product stewardship summary version. As much as 600,000 kilograms of carbon tetrachloride may have entered the soil column and a portion of this has contaminated the underlying aquifer. However, when heated to decomposition, it will emit fumes of extremely toxic phosgene and of hydrogen chloride.
The us epas drinking water regulations and contaminants. Sigmaaldrich offers a number of carbon tetrachloride solution products. Ccl 4 has become a model for the study of agents that cause localized cellular injury via a freeradical mechanism. The problem formulation document will be available for comment until august 16, 2018 in the docket epahqoppt20160733 return to the risk evaluation page for carbon tetrachloride. Carbon monoxide monosulfide, carbon oxide sulfide, carbon oxysulfide, dithiocarbonic anhydride, oxycarbon sulfide 1. Ccl 4 was once widely used as a dry cleaning solvent, precursor to refrigerant synthesis, propellant for aerosol cans, a fire extinguishing liquid, as a solvent for oils, fats, and lacquers, as a grain fumigant and curiously enough, in lava lamps 30, 31. Carbon tetrabromide material safety data sheet cas no 558. Carbon tetrachloride has a mutagenic effect and induces aneuploidy in several invitro systems. Liquid carbon dioxide co2 safety data sheet sds p4573 praxair.
Compressed carbon dioxide gas co2 sds safety data sheet p. It is also called carbon chloride, methane tetrachloride, perchloromethane, tetrachloroethane, or benziform. Respiratory depression and cardiac dysrhythmias are an immediate threat to life. Download the ntp report on carbon tetrachloride in pdf format 166k download. Safety data sheet creation date 24nov2010 revision date 18jan2018 revision number 3 1. Liquiflow liquid carbon dioxide, medipure liquid carbon dioxide. Carbon tetrachloride hepatotoxicity pharmacological. The possibility of replacing carbon tetrachloride by other available solvents hexane, petroleum ether, and mixtures of these compounds with ethyl alcohol for extraction of oiling agents used in the chemical fibre industry was investigated. In large fires where leakage may occur, water spray may be used if applied in quanitities sufficient to absorb the heat of reaction. Ac148170025 synonyms tetrachloromethane recommended use laboratory chemicals.
Dec 31, 2017 chronic exposure to carbon tetrachloride ccl4 a and sometimes acute exposure to very high concentrations a produces liver and kidney damage. This monograph is one in a series of selfinstructional. Meaning, pronunciation, translations and examples log in dictionary. A meta description is an html tag in the html code of your website, which allows you to customize a section of text that describes the page itself. Carbon tetrachloride ccl 4, a volatile inorganic compound, is a very welldescribed hepatotoxicant. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Until 1986, the chemical was used as a grain fumigant. Carbon tetrachloride ccl 4 is regarded as highly toxic. The international programme on chemical safetys report on carbon tetrachloride. Carbon tetrachloride ii disclaimer the use of company or product names is for identification only and does not imply endorsement by the agency for toxic substances and disease registry. Sw846 test methods for hazardous waste and solid waste, guidance and download.
How it works in situ bioremediation for the hanford carbon tetrachloride plume isb, which is the term used in this. Carbon tetrachloride definition and meaning collins. Sep 26, 2019 toxicological profile for carbon tetrachloride. All atsdr toxicological profile pdf files are electronic conversions from paper copy or other electronic ascii text files. It is highly recommend that you seek the material safety datasheet for this chemical from a reliable source such as siri, and follow its directions. Niosh considers carbon tetrachloride to be a potential occupational carcinogen as defined by the osha carcinogen policy 29 cfr 1990. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Chemical product and company identification product name. It is reasonably anticipated to be a human carcinogen, based on sufficient evidence of carcinogenicity from studies in experimental animals. The handling of this chemical may incur notable safety precautions. You may need a pdf reader to view some of the files on this page. Relevant identified uses of the substance or mixture and uses advised against use of the substancemixture. Identification of the substancemixture and of the companyundertaking.
Occupational exposure to carbon tetrachloride may occur in the chemical industry, in laboratories, and during degreasing operations. Carbon tetrachloride is most often found in the air as a colorless gas. Carbon tetrachloride an overview sciencedirect topics. It is a clear liquid with a sweet smell that can be detected at low levels. Sds of carbon tetrachloride, safety data sheets, cas 56235. In a prospective cohort study seidler 1999, the association between maternal occupational exposure to specific chemical substances among these carbon tetrachloride and the birth of smallforgestationalage sga infants was evaluated. Entry in the material safety data sheet hyperglossary at ilpi. Bioconcentration factor predicted from water solubility 14. Liver irregularities based on human evidence carbon tetrabromide section 12. Carbon bisulfide safety data sheet ghs product identifier other means of identification 24hour telephone section 1. The tclp, or toxicity characteristic leaching not leachate procedure is designed to determine the mobility of both organic and inorganic analytes present in liquid, solid, and multiphasic wastes. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Safety data sheet rochester institute of technology. It was shown that the solvent selected for extraction of the oiling agent is determined by both the structure of the fibre and the composition of.
Carbon tetrachloride is a volatile liquid, meaning. It was shown that the solvent selected for extraction of the oiling agent is determined by both the structure of the fibre and. Show this safety data sheet to the doctor in attendance. It is a known animal carcinogen and a potential human carcinogen. Carbon tetrachloride is a chlorinated organic solvent. Carbon tetrachloride induces hepatic cell proliferation and dna synthesis. Carbon tetrachloride is a clear, nonflammable liquid which is almost insoluble in water. Possible replacement of carbon tetrachloride with other. In particular, for carbon tetrachloride poisoning, at a time when liver triglycerides are increasing rapidly, there is no increase in flux of fatty acids through the plasma compartment.
In order to promote public education and public safety, equal justice for all, a better informed citizenry, the rule of law, world trade and world peace, this legal document is hereby made available on a noncommercial basis, as it is the right of all humans to know and speak the laws that govern them. Small fires close to stored silicon tetrachloride may be extinguished using carbon dioxide, dry chemical extinguishers, or dry sand, properly applied. Standard test method for carbon tetrachloride activity of. Since a major fraction of absorbed carbon tetrachloride is exhaled in first hour, good tidal volumes should be maintained in severely.
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